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Istanbul, Turkey, March 15-17, 2006

Prevention and control of perinatal hepatitis B virus (HBV) transmission in the WHO European Region

Overall goal fo the meeting

To contribute to further prevention and control of perinatal hepatitis B virus (HBV) transmission in the countries of the European Region of the World Health Organization (WHO), by highlighting the advantages of newborn hepatitis B vaccination based on scientific evidence, and by sharing examples, experience, and knowledge regarding prevention of mother-to-child transmission of HBV.

Wednesday, March 15, 2006

Session 1 Opening and objectives

Chair: Nedret Emiroglu and Ludmila Mosina


Session 2 Epidemiology of perinatal HBV transmission

Chair: Nedret Emiroglu and Ludmila Mosina

Hepatitis B disease burden: a model for global estimates and impact of vaccination 132 Kb (.pdf) загрузите русскую версию
Susan Wang, Atlanta, Georgia, USA

Magnitude of perinatal HBV transmission in the Central Asian Republics 1,659 Kb (.pdf)  загрузите русскую версию
Ludmila Mosina, Atlanta, Georgia, USA
Overview of HBV Infections and the vaccination policy in Turkey 532 Kb (.pdf)  загрузите русскую версию
Meral Çiblak and Selim Badur, Istanbul, Turkey

Coffee break

Session 3  Scientific evidence on control and prevention of perinatal HBV transmission through immunisation

Chair: Andrei Lobanov and Wolfgang Jilg

Effectiveness of newborn hepatitis B vaccination programmes in achieving a reduction of chronic carriage – timing of the birth dose – administration of HBIg: a review  1,097 Kb (.pdf) загрузите русскую версию
Francis André, Belgium

Are immunogenicity and protective efficacy of hepatitis B vaccine related to different administration schedules? 625 Kb (.pdf) загрузите русскую версию
Voranush Chongsrisawat, Bangkok, Thailand

Long term efficacy of hepatitis B vaccination of newborns from HBs Ag positive mothers in Thailand 58 Kb (.pdf) загрузите русскую версию
Bernard Hoet, Belgium

12.05- 14.00
Session 4 Prevention and control of perinatal HBV transmission: country status and experiences

Chair: Michael Favorov and Paolo Bonanni

Prevention of perinatal HBV transmission: evaluation of programmes and success stories from the Central Asian Republics – an example from Kazakhstan 1,826 Kb (.pdf) загрузите русскую версию
Michael Favorov, Atlanta, Georgia, USA

Experience from Armenia 968 Kb (.pdf) загрузите русскую версию
Armen Hayrapetyan, Armenia

Experience from Georgia 656 Kb (.pdf) загрузите русскую версию
Paata Imnadze, Georgia

Experience from Kyrgyzstan 265 Kb (.pdf) загрузите русскую версию
Joldosh Kalilov, Kyrgyzstan

Experience from Tajikistan 874 Kb (.pdf) загрузите русскую версию
Shamsiddin Jabirov, Tajikistan

Experience from Uzbekistan 1,943 Kb (.pdf) загрузите русскую версию
Erkin Musabaev, Uzbekistan

Thursday, March 16, 2006

SESSION 5  Prevention and control of perinatal HBV transmission: country status and experiences  – continued

Chair: Daniel Lavanchy and John Ward

Hepatitis B vaccination of newborns in rural China: evaluation of an outside-the-cold-chain delivery strategy 590 Kb (.pdf) загрузите русскую версию
Lixia Wang, Beijing, PR China

Improving the hepatitis B birth dose in Indonesia, Vietnam, and Cambodia 1,015 Kb (.pdf) загрузите русскую версию
Carib Nelson, Seattle, United States

WHO recommendations and guidelines for the prevention of perinatal hepatitis B and use of hepatitis B vaccines 288 Kb (.pdf) загрузите русскую версию
Steven Wiersma, Geneva, Switzerland

Session 6 Mother-and-child Health

Chair: Daniel Lavanchy and John Ward

Hepatitis B vaccination and HBIg administration policies implemented for premature babies – vaccines concurrently administered with the hepatitis B vaccine birth dose 531Kb (.pdf) загрузите русскую версию
Vassiliki Papaevangelou, Athens, Greece

Introduction to the workshops
Pierre Van Damme, Antwerpen, Belgium


Session 7 Workshops on how to prevent perinatal HBV transmission

Chair workgroup A: Andrei Lobanov and Michael Favorov
Chair workgroup B: Selim Badur and Daniel Shouval

Topics discussed in the workshops:
- Results from the country questionnaire: current situation, thresholds, evaluation methods, indicators used, …
- How do countries monitor the administration of the first dose and the timeliness of the first dose?
- Is there information available regarding the price per dose of hepatitis B vaccine your country is currently paying?
- What are the three most important contraindications for hepatitis B vaccination of newborns?
- Management of waste disposal.
- Storing hepatitis B vaccine at the recommended temperature.
- Country experiences: lessons learnt, opportunities, and outreach systems.
- How can hepatitis B vaccination fit into overall mother-and-child health programmes?
- Contraindications for newborn hepatitis B immunisation – examples from participating countries.

Friday, March 17, 2006

Session 8 Feedback form the workshops

Chair: Alessandro Zanetti and Harold Margolis

What is feasible? What are the thresholds? What is to be recommended and what is to be improved?  How should be communicated in this context at country level? What is needed in terms of advocacy? Lessons learnt. How to implement the recommendations.

Feedback from Workshop 1

Feedback from Workshop 2

Session 9 Conclusions of the meeting and closing remarks

Chair: Mark Kane and Steven Wiersma

Conclusions and summary of the meeting 123 Kb (.pdf)  загрузите русскую версию
David FitzSimons,  Geneva, Switzerland

11.30 Close of the meeting