VHPB Centre for Evaluation of Vaccination (CEV) |
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Meeting objectives:
Viral hepatitis treatment as prevention (TAP)
Background document TAP I (Pdf, kB)
Background document TAPII (Pdf, kB)
Thursday 15th of October 2020
PART 1 - TREATMENT AS PREVENTION (TAP) HEPATITIS C IN RISK GROUPS
Welcome and opening of the meeting
Chairs: Mojca Matitic & Pierre Van Damme
16:30 - 16:50 Welcome and opening of the meeting (Pdf, 324 kB)
Introduction of the VHPB Board & participants
1. Hepatitis treatment as prevention in risk groups
Session 1.1: Real-life data of TAP in different risk groups
16:50 - 17:10 Treatment as prevention in risk groups: an overview (Pdf, 3.637 kB)
Mojca Matitic
17:10 - 18:25 Treat all or Treatment as prevention in Risk groups
17:10 - 17:25 Modelling the potential prevention benefits of a treat-all hepatitis C treatment strategy at global, regional and country levels: A modelling study (Pdf, 505 kB)
Adam Trickey
PWID - Model of care and outcomes in PWID
17:25 - 17:40 Iceland Treatment as Prevention for Hepatitis C (TraP Hep C) - a nationwide elimination programme in Iceland using direct-acting antiviral agents. (Pdf, 2.069 kB)
Magnus Gottfredsson
17:40 - 17:55 Scotland Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) - a natural experiment (protocol). (Pdf, 1.905 kB)
Matthew Hickman
Prisoners – model of care and outcomes in PWID and prisoners (No speaker, included in the review of Mojca Maticic).
17:55 - 18:10 MSM - Model of care and outcomes in MSM
The Netherlands – Declining Hepatitis C Virus (HCV) Incidence in Dutch Human Immunodeficiency Virus-Positive Men Who Have Sex With Men After Unrestricted Access to HCV
Anders Boyd
17:10 - 18:25 Lessons Learned from HIV TAP program
Treatment as Prevention: Should Hepatitis C Learn the Lessons from HIV? (Pdf, 2.128 kB)
José Vincent Fernandez-Montero
Session 1.2: Groups discussion: hepatitis treatment as prevention
18:30 - 19:30 Groups discussion: hepatitis TAP be included in public health guidelines and recommendations
Questions to be answered:
1. Is there enough scientific evidence to include TAP in hepatitis prevention guidelines in all risks group or in some?
Chair: Thomas Vanwolleghem
2. Should TAP be included in the national hepatitis elimination plan? (responsibilities – resources)
Chair: Daniel Lavanchy
3. Should TAP in risks groups be included in WHO’s targets to achieve hepatitis Elimination by 2030? Is Micro elimination the way to go?
Chair: Antons Mozalevskis
Report - TAP in risk groups
Thursday 22 October 2020
PART II - TREATMENT AS PREVENTION (TAP)
2. Treatment as to prevent perinatal mother to child transmission (MTCT) of hepatitis B – Liver disease progression
16:30 - 16:45 Welcome and opening of the meeting (Pdf, 342 kB)
Introduction of the VHPB Board & participants
2.1. Treatment as to prevent perinatal mother to child transmission (MTCT) of hepatitis B
Session 2.1.1: Overview TAP in MTCT
Chairs: Antons Mozalevskis and Mark Kane
Conclusions of Pre-recorded presentation
16:45 - 16:55 Who to treat
Prevention of perinatal hepatitis B virus transmission. (135.455 MP4)
Kelvin Cheung
16:55 - 17:10 Efficacy and Safety of TAP In pregnancy
Efficacy and safety of antiviral prophylaxis during pregnancy to prevent mother-to-child transmission of hepatitis B virus: a systematic review and meta-analysis. (Pdf, 2.722 kB)
Yusuke Shimakawa
Cost-effectiveness (see later)
Session 2.1.2: Guidelines and recommendation for TAP in MTCT
17:10 - 17:25 Lessons learnt from Treatment as prevention in real world (Western Pacific)
Progress Toward Hepatitis B Control and Elimination of Mother-to-Child Transmission of Hepatitis B Virus - Western Pacific Region, 2005-2017. (350.248 MP4)
Rania Tohme
17:25 - 17:40 New recommendations on HBV prevention of mother-to-child transmission and the use of NUCs as an additional PMTCT intervention. (Pdf, 1.303 kB)
Antons Mozalevskis
17:40 - 17:55 Cost-effectiveness
Mother-to-child transmission of hepatitis B: What more needs to be done to eliminate it around the world.
Shevanthi Nayagam
Session 2.1.3: Groups discussion: hepatitis treatment as prevention
17:55 - 18:35 Groups discussion: hepatitis TAP be included in guidelines and recommendations
Questions to be answered:
2.2. Treatment to prevent liver disease progression
Session 2.2.1: Overview treatment to prevent liver disease progression in HbsAg positives
18:35 - 18:50 Conclusions of Pre-recorded presentation
Evidence for application of treatment to prevent liver disease progression in hepatitis B. (Pdf, 1.544 kB)
Homie Razavi
Country example Uzbekistan
Toward Hepatitis B and Hepatitis C Elimination Using a Catalytic Funding Model - Tashkent, Uzbekistan. (19.883 MP4)
Shakhlo Sadirova
Session 2.2.2: Groups discussion: hepatitis treatment as prevention liver disease progression
18:50 - 19:30 Groups discussion: hepatitis TAP be included in guidelines and recommendations
Questions to be answered:
The report of the meeting will be availabe soon.