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Antwerp, Belgium, March 12-13, 2009
Thursday, March 12, 2009
Session 1: Opening and objectives
Chair: Paolo Bonanni, Steven Wiersma
Hepatitis A
Session 2: Has the time come to control hepatitis A globally?
Chair: Paolo Bonanni, Steven Wiersma
08.50 – 09.20
Summary of major findings and conclusions of Global Hepatitis A meeting, Miami dec. 2007. 563Kb (.pdf)
Pierre Van Damme (UA Antwerpen, Belgium)
09.20 – 09.40
What are the risk factors with an impact on fatality rate in fulminant hepatitis A? 537Kb (.pdf)
Daniel Shouval (Hadassah-Hebrew University Hospital, Jerusalem, Israel)
09.40 – 09.25 Discussion
09.55 – 10.10 Coffee break
Session 3: Update on Hepatitis A epidemiology, prevention and control
Chair: Daniel Shouval, Vana Papaevangelou
3a. Epidemiology
10.10 – 10.25
Increase in Hepatitis A cases in the Czech Republic in 2008. 270Kb (.pdf)
J Cástková,(National Institute of Public Health, Prague, Czech Republic)
10.25 – 10.40
Community-wide outbreak of Hepatitis A in Latvia. 2.8Mb (.pdf)
J Perevoscikovs (Public Health Agency, Riga, Latvia)
10.40 – 10.50 Discussion
3b. Prevention
10.50 – 11.05
Long-term immunity induced by hepatitis A vaccines: an update. 264Kb (.pdf)
Koen Van Herck (UA Antwerpen, Belgium)
11.05 – 11.20
Correlation between humoral and cellular immune responses and the expression of the hepatitis A receptor HAVcr-1 on T cells after Hepatitis A vaccination in high and low responder. 772Kb (.pdf)
Ursula Wiedermann (Medical University, Vienna, Austria)
11.20 – 11.30 Discussion
3c. Control
11.30 – 11.45
EVENT, a network for harmonization typing of HAV and for alerting on hepatitis A outbreaks 111Kb (.pdf)
Helene Norder (SMI , Stockholm, Sweden)
11.45 – 12.05
Global overview on the effectiveness of Hepatitis A vaccination programs Hepatitis A vaccination in high and low responder. 623Kb (.pdf)
Umid Sharapov (CDC, Atlanta, USA)
12.05 – 13.05 Lunch
Chair:Rui Marinho, John Ward
13.05 – 13.25
Update on Hepatitis A epidemiology and prevention in WHO European Region. 132Kb (.pdf)
David Mercer (WHO Euro region)
13.25 – 13.45
Review of the Hepatitis A WHO position paper: need for an update? 196Kb (.pdf)
Steven Wiersma (WHO)
13.45 – 14.00 Discussion on Hepatitis A lessons learned and future initiatives
Hepatitis E
Session 4: Introduction on Hepatitis E
Chair: Alessandro Zanetti, Selim Badur
14.10 – 14.40
Hepatitis E from A to Z: Discovery and Characterization. 2.9Mb (.pdf)
Robert Purcell (National Institutes of Health, Maryland,USA)
14.40 – 14.55 Coffee break
Session 5: Virology, pathogenesis and natural history
Chair: Alessandro Zanetti, Selim Badur
14.55 – 15.15
Molecular epidemiology of hepatitis E, taxonomy, molecular biology,genotypes and subtypes. 299Kb(.pdf)
Helene Norder (SMI , Stockholm, Sweden)
15.15 – 15.35
Pathogenesis and natural history of hepatitis E. 1.1Mb (.pdf)
Krzysztof Krawczynski (CDC, Atlanta, USA)
15.35 – 15.50 Discussion
Session 6: Zoönotic transmission of HEV
Chair: Pierre Van Damme, Francoise Roudot-Thoraval
15.50 – 16.10
Hepatitis E: a curious zoönosis. 753Kb (.pdf)
Nicole Pavio (AFSSA LERPA-ENVA-INRA, Ecole Nationale Veterinaire d’alfort, France )
16.10 – 16.30
Distribution of hepatitis E virus in the environment. 999Kb (.pdf)
Rosina Girones (University of Barcelona, Spain)
16.30 – 16.45
Endemic HEV in Europe.
Erwin Duizer (RIVM, Bilthoven, The Netherlands)
16.45 – 17.00 Discussion
17.00 End meeting day 1
18.30 Drink at the Town hall
20.00 Dinner
Friday, March 13, 2009
Session 5 (continu): Virology, pathogenesis and natural history
Chair: Daniel Lavanchy, Hal Margolis
09.00 – 09.20
Hepatitis E virus and chronic hepatitis in organ-transplant recipients. 1.4Mb (.pdf)
Nassim Kamar (Centre Hospitalier Universitaire, Rangueil, France)
Session 7: Hepatitis E and its emergence in (non-)endemic areas
Chair: Daniel Lavanchy, Hal Margolis
09.20 – 09.35 UK
Autochthonous hepatitis E in Southwest England. 461Kb (.pdf)
Harry R Dalton (Royal Cornwall Hospital Trust, UK)
09.35 – 09.50 The Netherlands
Non-travel related Hepatitis E virus infections in the Netherlands. 472Kb (.pdf)
Erwin DuizerRIVM, Bilthoven, The Netherlands)
09.50 – 10.05 France
Acute hepatitis E in south-west France over a 5-year period. 655Kb (.pdf)
Jean Michel Mansuy (CHU Toulouse, France)
10.05 – 10.20 Germany
Hepatitis E Virus Infection in Germany. 173Kb (.pdf)
Wolfgang Jilg (University of Regensburg, Germany)
10.20 – 10.35 Spain
Prevalence of hepatitis E virus infection in children in Northeast of Spain. 138Kb (.pdf)
Maria Buti - presented by Rosina Girones (University of Barcelona, Spain)
10.35 – 10.50 Coffee break
Chair: Koen Van Herck, Mark Kane
10.50 – 11.05 Italy
Hepatitis E in Italy. 361Kb (.pdf)
Alessandro Zanetti (University of Milan, Italy)
11.05 – 11.20
The seroprevalence of HEV in the National Health and Nutrition Sample of the United States population. 647Kb (.pdf)
Kenrad Nelson> (John Hopkins School of Medicine, Baltimore, Maryland,USA)
11.20 – 11.40
Hepatitis E in Asian Region. 3.9Mb (.pdf)
Emily Gurley (Infectious Disease and Vaccine Sciences Program, Dhaka,Bangladesh)
11.40 – 12.00 Discussion
Session 8: Vaccine against HEV and its future
Chair: Koen Van Herck, Mark Kane
12.00 – 12.20
Safety and efficacy of a recombinant hepatitis E vaccine. 194Kb (.pdf)
Bruce Innis(GSK, Philadelphia, USA)
12.20 – 12.40
Hepatitis E vaccine: Clinical experience. 717Kb (.pdf)
Mrigendra Shrestha (institute Walter Reed/ AFRIMS Research Unit Nepal, Nepal)
12.40 – 13.00
Randomized-controlled phase II clinical trial of a bacterially expressed recombinant hepatitis E vaccine. 1Mb (.pdf)
JamesWai-kuo Shih (National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen , China)
13.00 – 13.15 Discussion
13.15 – 14.45 Lunch
Session 9: Conclusions of the meeting
Chair: Johannes Hallauer, Wolfgang Jilg
14.00 – 15.00
Presentation of the VHPB meeting conclusions. 133Kb (.pdf)
D. FitzSimons
15.00 Close of the meeting